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I'm running on a vps and ram space is tight.  I have stopped clamav and that free'd up about 300mb. Perfect. 
service clam-av stop
but how do I make this change perm. on boot?

I found Zhang's answer below, but it is now to old to be relevant as the file no longer exists.  I found the line in 50-user but changing it did not stop clamav from starting at bootup.

1) Disable ClamAV services (clamd, freshclamd)
2) Uncomment out below line in /etc/amavisd.conf, and set it to 0. Then restart Amavisd service.
@bypass_virus_checks_maps = (0);  # controls running of anti-virus code
That's all