We have a document for you:
http://www.iredmail.org/docs/errors.htm … -logged-in

Hey, @ZhangHuangbin 

I did as recommend at the link:

main.cf
smtpd_sender_restrictions = reject_unknown_sender_domain, reject_non_fqdn_sender, reject_unlisted_sender, permit_mynetworks, permit_sasl_authenticated

still the same problem.

I have also try
smtpd_sender_restrictions =

Still the same issue get  return email.

Sender address rejected: not logged in (in reply  to RCPT TO command)

Ok, I am using Roundcube which is packaged with the iRedadmin.  I installed following the instruction. I have installed iRedamin before 0.9.2  without this problem. 

The configuration for roundcube seems to have SMTP authen as 'LOGIN'

config/config.inc.php
// SMTP
$config['smtp_server'] = 'tls://127.0.0.1';
$config['smtp_port'] = 587;
$config['smtp_user'] = '%u';
$config['smtp_pass'] = '%p';
$config['smtp_auth_type'] = 'LOGIN';
// Required if you're running PHP 5.6
$config['smtp_conn_options'] = array(
    'ssl' => array(
        'verify_peer'      => false,
        'verify_peer_name' => false,
    ),
);