==== REQUIRED BASIC INFO OF YOUR IREDMAIL SERVER ====
- iRedMail version (check /etc/iredmail-release): 0.9.9
- Deployed with iRedMail Easy or the downloadable installer? downloadable installer
- Linux/BSD distribution name and version:  Debian 8.3
- Store mail accounts in which backend (LDAP/MySQL/PGSQL): LDAP
- Web server (Apache or Nginx): Nginx
- Manage mail accounts with iRedAdmin-Pro? Yes
- [IMPORTANT] Related original log or error message is required if you're experiencing an issue.
====

Can't find much interesting in error logs, other than this in syslog

Any suggestions?

Feb  6 17:40:11 hostname uwsgi: Traceback (most recent call last):#012 
File "/usr/lib/python2.7/dist-packages/web/application.py", line 239, in process#012    return self.handle()#012 
File "/usr/lib/python2.7/dist-packages/web/application.py", line 230, in handle#012    return self._delegate(fn, self.fvars, args)#012 
File "/usr/lib/python2.7/dist-packages/web/application.py", line 420, in _delegate#012    return handle_class(cls)#012 
File "/usr/lib/python2.7/dist-packages/web/application.py", line 396, in handle_class#012    return tocall(*args)#012 
File "/opt/www/iRedAdmin-Pro-LDAP-3.3/controllers/ldap/user.py", line 293, in GET#012   
_qr = mlmmj.get_subscribed_lists(mail=mail, query_all_lists=False)#012
File "/opt/www/iRedAdmin-Pro-LDAP-3.3/libs/mlmmj/__init__.py", line 338, in get_subscribed_lists#012   
r = requests.get(url, params=params, headers=api_headers, verify=_verify_ssl)#012 
File "/usr/lib/python2.7/dist-packages/requests/api.py", line 70, in get#012   
return request('get', url, params=params, **kwargs)#012 
File "/usr/lib/python2.7/dist-packages/requests/api.py", line 56, in request#012   
return session.request(method=method, url=url, **kwargs)#012 
File "/usr/lib/python2.7/dist-packages/requests/sessions.py", line 475, in request#012    resp = self.send(prep, **send_kwargs)#012 
File "/usr/lib/python2.7/dist-packages/requests/sessions.py", line 596, in send#012   
r = adapter.send(request, **kwargs)#012 
File "/usr/lib/python2.7/dist-packages/requests/adapters.py", line 487, in send#012   
raise ConnectionError(e, request=request)#012
ConnectionError: HTTPConnectionPool(host='127.0.0.1', port=7790): Max retries exceeded with url: /api/subscriber/bob@hope.com/subscribed?query_all_lists=no&email_only=no (Caused by NewConnectionError('<requests.packages.urllib3.connection.HTTPConnection object at 0x7f038fa24750>: Failed to establish a new connection: [Errno 111] Connection refused',))
Feb  6 17:40:11 hostname uwsgi:
Feb  6 17:40:11 hostname uwsgi: domain [pid: 30430|app: 1|req: 74/94] remote host ip () {50 vars in 1104 bytes} [Wed Feb  6 17:40:11 2019] GET /iredadmin/profile/user/general/bob@hope.com => generated 21 bytes in 52 msecs (HTTP/1.1 500) 2 headers in 164 bytes (2 switches on core 0)