Here is my config file:  This is for my owncloud instance, both are identical and neither is working.  The sockets are present and netstat -a reveals they are listening.  Any help?

        rewrite ^/owncloud$ /owncloud/ redirect;

    location /owncloud/ {
        root /var/www/html/owncloud/;

        # Add headers to serve security related headers
        # Before enabling Strict-Transport-Security headers please read into this topic first.
        # add_header Strict-Transport-Security "max-age=15768000; includeSubDomains; preload;";
        add_header X-Content-Type-Options nosniff;
        add_header X-Frame-Options "SAMEORIGIN";
        add_header X-XSS-Protection "1; mode=block";
        add_header X-Robots-Tag none;
        add_header X-Download-Options noopen;
        add_header X-Permitted-Cross-Domain-Policies none;
        add_header Strict-Transport-Security "max-age=15552000; includeSubDomains";

        # set max upload size
        client_max_body_size 10G;
        fastcgi_buffers 64 4K;

        # Disable gzip to avoid the removal of the ETag header
        gzip off;

        # Uncomment if your server is build with the ngx_pagespeed module
        # This module is currently not supported.
        #pagespeed off;

        index index.php;

        error_page 403 /owncloud/core/templates/403.php;
        error_page 404 /owncloud/core/templates/404.php;

        location ~ ^/owncloud/apps-appstore/(.*)$ {
            alias /var/lib/owncloud/apps/$1;
        }

        location ~ ^/owncloud/assets/(.*)$ {
            alias /var/lib/owncloud/assets/$1;
        }

        location ~ ^/owncloud/(build|tests|config|lib|3rdparty|templates|data)/ {
            deny all;
        }

        location ~ ^/owncloud/(?:\.|autotest|occ|issue|indie|db_|console) {
            deny all;
        }

        rewrite ^/owncloud/remote/(.*) /owncloud/remote.php last;
        rewrite ^/owncloud/core/doc/([^\/]+)(?:$|/) /owncloud/core/doc/$1/index.html;

        # try_files $uri $uri/ =404;
        try_files $uri $uri/ /owncloud/index.php;

        location ~ \.php(?:$|/) {
            fastcgi_split_path_info ^(.+\.php)(/.+)$;
            include fastcgi_params;
            fastcgi_param SCRIPT_FILENAME $document_root$fastcgi_script_name;
            fastcgi_param SCRIPT_NAME $fastcgi_script_name;
            fastcgi_param PATH_INFO $fastcgi_path_info;
            fastcgi_param HTTPS on;
            fastcgi_param modHeadersAvailable true; #Avoid sending the security headers twice
            fastcgi_pass unix:/var/run/php-fpm/owncloud.socket;
            fastcgi_intercept_errors on;
        }

        # Adding the cache control header for js and css files
        # Make sure it is BELOW the location ~ \.php(?:$|/) { block
        location ~* \.(?:css|js)$ {
            add_header Cache-Control "public, max-age=7200";
            # Optional: Don't log access to assets
            access_log off;
        }

        # Optional: Don't log access to other assets
        location ~* \.(?:jpg|jpeg|gif|bmp|ico|png|swf)$ {
            access_log off;
        }

        }

Thanks for the followup answer, Max