==== REQUIRED BASIC INFO OF YOUR IREDMAIL SERVER ====
- iRedMail version (check /etc/iredmail-release):
1.6.3 MARIADB edition.
- Deployed with iRedMail Easy or the downloadable installer?
with downloadable installer
- Linux/BSD distribution name and version:
Ubuntu latest
- Store mail accounts in which backend (LDAP/MySQL/PGSQL):
MySQL
- Web server (Apache or Nginx):
Nginx
- Manage mail accounts with iRedAdmin-Pro?
No
- [IMPORTANT] Related original log or error message is required if you're experiencing an issue.
====

I'm trying to send emails to other addresses, for some reason the messages don't arrive at the address, i think the problem is this "Connection timed out", but i dont understant why it occour,
After some searching i find this error normaly occour because of port 25 blocked by ISP, but it"s not my case

Jun 14 13:44:18 mail postfix/submission/smtpd[25504]: connect from localhost[127.0.0.1]
Jun 14 13:44:18 mail postfix/submission/smtpd[25504]: Anonymous TLS connection established from localhost[127.0.0.1]: TLSv1.3 with cipher TLS_AES_256_GCM_SHA384 (256/256 bits) key-exchange X25519 server-signature RSA-PSS (4096 bits) ser>Jun 14 13:44:18 mail postfix/submission/smtpd[25504]: 4QhB8f39Hkz4057: client=localhost[127.0.0.1], sasl_method=LOGIN, sasl_username=postmaster@rkgl.com.br
Jun 14 13:44:18 mail postfix/cleanup[25506]: 4QhB8f39Hkz4057: message-id=<a272d77a6d071c922c999b781a26da12@rkgl.com.br>
Jun 14 13:44:18 mail postfix/qmgr[2034]: 4QhB8f39Hkz4057: from=<postmaster@rkgl.com.br>, size=554, nrcpt=1 (queue active)
Jun 14 13:44:18 mail roundcube: <b7va325k> User postmaster@rkgl.com.br [192.168.4.12]; Message <a272d77a6d071c922c999b781a26da12@rkgl.com.br> for    *****@hotmail.com; 250: 2.0.0 Ok: queued as 4QhB8f39Hkz4057
Jun 14 13:44:18 mail postfix/submission/smtpd[25504]: disconnect from localhost[127.0.0.1] ehlo=2 starttls=1 auth=1 mail=1 rcpt=1 data=1 quit=1 commands=8
Jun 14 13:44:19 mail postfix/10025/smtpd[25513]: connect from localhost[127.0.0.1]
Jun 14 13:44:19 mail postfix/10025/smtpd[25513]: 4QhB8g2MxNz405K: client=localhost[127.0.0.1]
Jun 14 13:44:19 mail postfix/cleanup[25506]: 4QhB8g2MxNz405K: message-id=<a272d77a6d071c922c999b781a26da12@rkgl.com.br>
Jun 14 13:44:19 mail postfix/qmgr[2034]: 4QhB8g2MxNz405K: from=<postmaster@rkgl.com.br>, size=1784, nrcpt=1 (queue active)
Jun 14 13:44:19 mail postfix/10025/smtpd[25513]: disconnect from localhost[127.0.0.1] ehlo=1 mail=1 rcpt=1 data=1 quit=1 commands=5
Jun 14 13:44:19 mail amavis[10119]: (10119-05) Passed CLEAN {RelayedInternal}, ORIGINATING/MYNETS LOCAL [127.0.0.1]:46994 ESMTP/ESMTP <postmaster@rkgl.com.br> -> <   *****@hotmail.com>, (), Queue-ID: 4QhB8f39Hkz4057, Message-ID: <a272d>Jun 14 13:44:19 mail postfix/amavis/smtp[25507]: 4QhB8f39Hkz4057: to=<   *****@hotmail.com>, relay=127.0.0.1[127.0.0.1]:10026, delay=1.1, delays=0.19/0.01/0/0.91, dsn=2.0.0, status=sent (250 2.0.0 from MTA(smtp:[127.0.0.1]:10025): 250 >Jun 14 13:44:19 mail postfix/qmgr[2034]: 4QhB8f39Hkz4057: removed
Jun 14 13:44:49 mail postfix/smtp[25348]: connect to hotmail-com.olc.protection.outlook.com[104.47.66.33]:25: Connection timed out
Jun 14 13:45:19 mail postfix/smtp[25348]: connect to hotmail-com.olc.protection.outlook.com[104.47.55.161]:25: Connection timed out
Jun 14 13:45:19 mail postfix/smtp[25348]: 4QhB8g2MxNz405K: to=<   *****@hotmail.com>, relay=none, delay=60, delays=0.13/0.01/60/0, dsn=4.4.1, status=deferred (connect to hotmail-com.olc.protection.outlook.com[104.47.55.161]:25: Connect>Jun 14 13:46:42 mail postfix/qmgr[2034]: 4QhB4R0mggz405H: from=<postmaster@rkgl.com.br>, size=1785, nrcpt=1 (queue active)
Jun 14 13:46:42 mail postfix/qmgr[2034]: 4QhB4R0f4pz405G: from=<postmaster@rkgl.com.br>, size=1777, nrcpt=1 (queue active)
Jun 14 13:46:42 mail postfix/smtp[25584]: connect to gmail-smtp-in.l.google.com[2800:3f0:4003:c08::1b]:25: Network is unreachable
Jun 14 13:47:12 mail postfix/smtp[25348]: connect to hotmail-com.olc.protection.outlook.com[104.47.17.97]:25: Connection timed out
Jun 14 13:47:12 mail postfix/smtp[25584]: connect to gmail-smtp-in.l.google.com[172.217.192.26]:25: Connection timed out
Jun 14 13:47:12 mail postfix/smtp[25584]: connect to alt1.gmail-smtp-in.l.google.com[2a00:1450:400c:c0b::1b]:25: Network is unreachable
Jun 14 13:47:42 mail postfix/smtp[25348]: connect to hotmail-com.olc.protection.outlook.com[104.47.18.97]:25: Connection timed out
Jun 14 13:47:42 mail postfix/smtp[25348]: 4QhB4R0mggz405H: to=<   *****@hotmail.com>, relay=none, delay=424, delays=364/0.02/60/0, dsn=4.4.1, status=deferred (connect to hotmail-com.olc.protection.outlook.com[104.47.18.97]:25: Connecti>Jun 14 13:47:42 mail postfix/smtp[25584]: connect to alt1.gmail-smtp-in.l.google.com[64.233.184.26]:25: Connection timed out
Jun 14 13:47:42 mail postfix/smtp[25584]: connect to alt2.gmail-smtp-in.l.google.com[2a00:1450:4025:401::1b]:25: Network is unreachable
Jun 14 13:47:42 mail postfix/smtp[25584]: 4QhB4R0f4pz405G: to=<   *****@gmail.com>, relay=none, delay=424, delays=364/0.02/60/0, dsn=4.4.1, status=deferred (connect to alt2.gmail-smtp-in.l.google.com[2a00:1450:4025:401::1b]:25: Network i>Jun 14 13:51:42 mail postfix/qmgr[2034]: 4QhB6N2jqgz405J: from=<postmaster@rkgl.com.br>, size=1780, nrcpt=1 (queue active)
Jun 14 13:51:42 mail postfix/qmgr[2034]: 4QhB8g2MxNz405K: from=<postmaster@rkgl.com.br>, size=1784, nrcpt=1 (queue active)
Jun 14 13:51:42 mail postfix/qmgr[2034]: 4Qh6D548Nnz4059: from=<postmaster@rkgl.com.br>, size=1784, nrcpt=1 (queue active)
Jun 14 13:52:12 mail postfix/smtp[25741]: connect to hotmail-com.olc.protection.outlook.com[104.47.57.33]:25: Connection timed out
Jun 14 13:52:12 mail postfix/smtp[25740]: connect to hotmail-com.olc.protection.outlook.com[104.47.57.33]:25: Connection timed out
Jun 14 13:52:12 mail postfix/smtp[25739]: connect to gmail-smtp-in.l.google.com[142.251.0.27]:25: Connection timed out
Jun 14 13:52:12 mail postfix/smtp[25739]: connect to gmail-smtp-in.l.google.com[2800:3f0:4003:c03::1a]:25: Network is unreachable
Jun 14 13:52:12 mail postfix/smtp[25739]: connect to alt1.gmail-smtp-in.l.google.com[2a00:1450:400c:c0b::1a]:25: Network is unreachable
Jun 14 13:52:42 mail postfix/smtp[25741]: connect to hotmail-com.olc.protection.outlook.com[104.47.56.33]:25: Connection timed out
Jun 14 13:52:42 mail postfix/smtp[25739]: connect to alt1.gmail-smtp-in.l.google.com[64.233.184.26]:25: Connection timed out
Jun 14 13:52:42 mail postfix/smtp[25740]: connect to hotmail-com.olc.protection.outlook.com[104.47.56.33]:25: Connection timed out
Jun 14 13:52:42 mail postfix/smtp[25741]: 4Qh6D548Nnz4059: to=<   *****@hotmail.com>, relay=none, delay=11141, delays=11081/0.03/60/0, dsn=4.4.1, status=deferred (connect to hotmail-com.olc.protection.outlook.com[104.47.56.33]:25: Conn>Jun 14 13:52:43 mail postfix/smtp[25740]: 4QhB8g2MxNz405K: to=<   *****@hotmail.com>, relay=none, delay=503, delays=443/0.03/60/0, dsn=4.4.1, status=deferred (connect to hotmail-com.olc.protection.outlook.com[104.47.56.33]:25: Connecti>